Experimental hydrophobicity parameters of perfluorinated alkylated substances from reversed-phase high-performance liquid chromatography

“Capacity factors of perfluorinated alkylated substances were obtained from isocratic reversed-phase high-performance liquid chromatography–mass spectrometry experiments at different organic modifier strengths of the mobile phase. The resulting capacity factor v. modifier strengths plots were extrapolated to obtain capacity factors at 100 % water (k0) that can serve as indicators of the hydrophobicity of the perfluorinated acids. Values of log k0 were shown to increase linearly with the number of CF2 units in the fluorinated alkyl chain.”

(Citaat: Voogt, W.P. de, Zurano, L., et al., – Experimental hydrophobicity parameters of perfluorinated alkylated substances from reversed-phase high-performance liquid chromatography – Environmental Chemistry 9 (2012)6, p.564-570 – Open Access)